CD147 anticorps
Aperçu rapide pour CD147 anticorps (ABIN7860919)
Antigène
Voir toutes CD147 (BSG) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- CD147 / BSG / EMMPRIN / Neurothelin Antibody
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Specificité
- This MAb recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant full-length human BSG protein
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- CD147 (BSG) (Basigin (Ok Blood Group) (BSG))
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Autre désignation
- CD147
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Sujet
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5A11 Antigen, 5F7, Basigin, Blood brain barrier HT7 antigen BSG, Extracellular Matrix Metalloproteinase Inducer (EMMPRIN), Leukocyte Activation Antigen M6, Neurothelin, OK Blood Group Antigen, TCSF, Tumor Cell-derived Collagenase Stimulatory Factor
HeLa cells. Human renal cell carcinoma, ovarian carcinoma or melanoma. HepG2, MCF7, Brain, Heart, Liver
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Poids moléculaire
- 35kDa (non-reduced), 40kDa (reduced)
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ID gène
- 682, 501293
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UniProt
- P35613
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Pathways
- S100 Proteins
Antigène
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