Recombinant CA8 anticorps

N° du produit ABIN7860977

Cet anticorps Lapin Monoclonal détecte spécifiquement CA8 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant CA8 anticorps (ABIN7860977)

Antigène: CA8 (Carbonic Anhydrase VIII (CA8))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CA8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: CA8-8605R

Détail du produit anti-CA8 anticorps

Fonction: Recombinant Carbonic Anhydrase VIII Antibody

Specificité: The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in CA8 gene causes neuropathology, such as ataxia, mild mental retardation and the predisposition to quadrupedal gait. It is also associated with the development of colorectal and lung cancers. Additionally, it is upregulated in various cancers.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human CA8 protein

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur CA8

Antigène: CA8 (Carbonic Anhydrase VIII (CA8))

Autre désignation: Carbonic Anhydrase VIII

Sujet:

CA-VIII, CALS, CARP, MGC120502, MGC99509

Human cerebellum. Selective expression in Purkinje cells. HEK-293 or K-562 cell lines. Brain, Jurkat

Poids moléculaire: 32.97kDa

ID gène: 767, 654388