Recombinant CA8 anticorps

N° du produit ABIN7864862

L’anticorps anti-CA8 Monoclonal Souris est utilisé pour la détection de CA8 dans des échantillons de Humain. Il a été validé pour WB et IHC.

Aperçu rapide pour Recombinant CA8 anticorps (ABIN7864862)

Antigène: CA8 (Carbonic Anhydrase VIII (CA8))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CA8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: RCA8-8835

Détail du produit anti-CA8 anticorps

Fonction: Recombinant Carbonic Anhydrase VIII Antibody

Specificité: The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in CA8 gene causes neuropathology, such as ataxia, mild mental retardation and the predisposition to quadrupedal gait. It is also associated with the development of colorectal and lung cancers. Additionally, it is upregulated in various cancers.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human CA8 protein

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur CA8

Antigène: CA8 (Carbonic Anhydrase VIII (CA8))

Autre désignation: Carbonic Anhydrase VIII

Sujet:

CA-VIII, CALS, CARP, MGC120502, MGC99509

Human cerebellum. Selective expression in Purkinje cells. HEK-293 or K-562 cell lines. MCF7.

Poids moléculaire: 32.97kDa

ID gène: 767, 654388