Recombinant CPA1 anticorps
Aperçu rapide pour Recombinant CPA1 anticorps (ABIN7865170)
Antigène
Voir toutes CPA1 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Recombinant Carboxypeptidase A1 / CPA1 (Pancreatic Cancer Marker) Antibody
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Specificité
- Human pancreatic procarboxypeptidase A exists as three different active forms, two of which are designated carboxypeptidase A1 (CPA1) and carboxypeptidase A2 (CPA2). CPA1, also known as CPA, is a 419 amino acid secreted monomeric protein that is highly expressed in pancreatic tissue. Functioning as a pancreatic exopeptidase, CPA1 uses zinc as a cofactor to catalyze the release of C-terminal amino acids from a variety of proteins, thereby playing a key role in protein digestion and degradation. Via its catalytic activity, CPA1 is also thought to be involved in zymogen (proenzyme) inhibition, probably functioning to block enzyme activation pathways. Abnormal levels of CPA1 are associated with pancreatic cancer, suggesting a possible role in either tumor progression or tumor suppression events.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant full-length human CPA1 protein
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Isotype
- IgG, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- CPA1 (Carboxypeptidase A1 (Pancreatic) (CPA1))
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Autre désignation
- Carboxypeptidase A1
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Sujet
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Carboxypeptidase A1 (pancreatic), CPA1, Pancreatic Carboxypeptidase A1, Procarboxypeptidase A1 pancreatic
Pancreas.
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Poids moléculaire
- 47kDa
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ID gène
- 1357, 2879
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UniProt
- P15085
Antigène
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