CNOT10 anticorps

N° du produit ABIN7862878

Cet anticorps anti-CNOT10 Monoclonal Souris (Clone PCRP-CNOT10-1D5) (ABIN7862878) détecte spécifiquement CNOT10 dans WB, ELISA, IF et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CNOT10 anticorps (ABIN7862878)

Antigène: CNOT10 (CCR4-NOT Transcription Complex, Subunit 10 (CNOT10))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CNOT10 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-CNOT10-1D5

Détail du produit anti-CNOT10 anticorps

Fonction: CCR4-NOT transcription complex, subunit 10 (CNOT10) Antibody

Specificité: CNOT10 is a subunit of the CCR4-NOT complex which consists of at least five other CNOT subunit proteins and TAB182. The CCR4-NOT complex is an evolutionarily conserved, multi-component complex known to be involved in transcription, as well as in mRNA degradation. Various subunits (e.g. CNOT1, CNOT3) are uniquely involved in influencing nuclear hormone receptor activities. In effect, this complex has an important role as a transcription regulator and repressor of nuclear receptor signaling that is relevant to the molecular pathways involved in cancer. The CCR4-NOT complex is also involved in the regulation of Histone H3 lysine 4 methylation through a ubiquitin-dependent pathway that likely involves the proteasome.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human CNOT10 protein

Isotype: IgG2c

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur CNOT10

Antigène: CNOT10 (CCR4-NOT Transcription Complex, Subunit 10 (CNOT10))

Autre désignation: CCR4-NOT transcription complex, subunit 10

Sujet:

FLJ12890, FLJ13165

HeLa or HepG2 cells.

Poids moléculaire: 82.31kDa

ID gène: 25904, 444851

UniProt: Q9H9A5