Desmin anticorps

N° du produit ABIN7861205

Cet anticorps Souris Monoclonal détecte spécifiquement Desmin dans IHC. Il présente une réactivité avec des échantillons de Humain, Chien, Boeuf (Vache), Cheval et Cat.

Aperçu rapide pour Desmin anticorps (ABIN7861205)

Antigène: Desmin (DES)

Reactivité: Humain, Chien, Boeuf (Vache), Cheval, Cat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Desmin est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: DES-3255

Détail du produit anti-Desmin anticorps

Fonction: Desmin (Muscle Cell Marker) Antibody

Specificité: Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain °™-helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles.Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human desmin protein

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Desmin

Antigène: Desmin (DES)

Autre désignation: Desmin

Sujet:

CMD1I, CSM1, CSM2, DES, Intermediate filament protein

SJRH30 cells. Human uterus, small intestine or leiomyosarcoma.

Poids moléculaire: 52kDa

ID gène: 1674, 594952

UniProt: P17661