Fibronectin 1 anticorps
Aperçu rapide pour Fibronectin 1 anticorps (ABIN7862847)
Antigène
Voir toutes Fibronectin 1 (FN1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Fibronectin (Fibrin/Heparin-Binding Domain) Antibody
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Specificité
- Fibronectins are disulfide-linked, dimeric glycoproteins of ~440 kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Epitope of this MAb is located in the 29 kDa N-terminal fibrin- and heparin-binding domain of fibronectin. It does not cross-react with MMP-2, MMP-9, or TIMP-2. Fibronectins are involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- High molecular weight proteins secreted by cultivated human fibroblasts
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Isotype
- IgG2a, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- Fibronectin 1 (FN1)
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Autre désignation
- Fibronectin Fibrin
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Sujet
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Cold insoluble globulin (CIG), FINC, FN1, FNZ, GFND, GFND2, LETS, Migration stimulating factor (MSF), Ugl-Y3
SW156 cells. Prostate or Kidney.
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Poids moléculaire
- 220kDa (monomer), 440kDa (dimer)
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ID gène
- 2335, 203717
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UniProt
- P02751
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy
Antigène
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