GTF2H2C anticorps
Aperçu rapide pour GTF2H2C anticorps (ABIN7863485)
Antigène
Voir toutes GTF2H2C AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- GTF2H2C (Transcription Factor) Antibody
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Specificité
- Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFIIH. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of five subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34. Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and MAT1. Both p89 and p80 have ATP-dependent helicase activity. The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant full-length human GTF2H2C protein
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Isotype
- IgG2c
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- GTF2H2C (General Transcription Factor IIH, Polypeptide 2C (GTF2H2C))
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Autre désignation
- GTF2H2C
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Sujet
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EVR6, PFM14, PR domain zinc finger protein 17 (PRDM17), RP72, Zinc finger protein 408 (GTF2H2C)
HeLa or Raji cells. Human breast or prostate carcinoma.
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Poids moléculaire
- 44kDa
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ID gène
- 730394, 422901
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UniProt
- Q6P1K8
Antigène
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