Recombinant Keratin Acidic (AE1) anticorps

N° du produit ABIN7861617

L’anticorps anti-Keratin Acidic Monoclonal Souris est utilisé pour la détection de Keratin Acidic dans des échantillons de Humain, Rat, Poulet, Boeuf (Vache), Souris, Lapin, Singe, Chien et Tortue. Il a été validé pour IHC et WB.

Aperçu rapide pour Recombinant Keratin Acidic (AE1) anticorps (ABIN7861617)

Antigène: Keratin Acidic (AE1)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Rat, Poulet, Boeuf (Vache), Souris, Lapin, Singe, Chien, Tortue

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Clone: RKRTL-8751

Détail du produit

Fonction: Recombinant Cytokeratin, Acidic (Type I or LMW) (Epithelial Marker) Antibody

Specificité: This MAb recognizes the 56.5 kDa (CK10), 50 kDa (CK14), 50 kDa (CK15), 48 kDa (CK16), 40 kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50 , 48, 46, 45, and 40 kDa. MAb AE3 recognizes the 65-67, 64, 59, 58, 56, and 52 kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Human epidermal keratin

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détail du antigène

Antigène: Keratin Acidic (AE1)

Autre désignation: Cytokeratin, Acidic

Sujet:

K1B, KRT1B, Keratin, type II cytoskeletal 1b, K77, CK-1B, Keratin 1B, Keratin-77, Cytokeratin-1B, Type-II Keratin Kb39

Skin or squamous cell carcinoma (IHC). A431.

Poids moléculaire: 40-56.5kDa

ID gène: 374454, 334989