MUC5AC anticorps
Aperçu rapide pour MUC5AC anticorps (ABIN7861757)
Antigène
Voir toutes MUC5AC AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Fonction
- MUC5AC (Mucin 5AC / Gastric Mucin) Antibody
-
Specificité
- This MAb recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC). Its epitope is located in the C-terminal cysteine rich part of the peptide core of MUC5AC. Its epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.
-
Purification
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
-
Immunogène
- M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient
-
Isotype
- IgG1, kappa
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 200 μg/mL
-
Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C
-
Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
Date de péremption
- 24 months
-
-
- MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))
-
Autre désignation
- MUC5AC Mucin 5AC
-
Sujet
-
Apomucin Major Airway Glycoprotein, Mucin 5 subtype AC tracheobronchial, Mucin 5 Subtypes A And C, Mucin 5AC oligomeric mucus/gel forming, Tracheobronchial Mucin (TBM)
Stomach
-
Poids moléculaire
- 400-600 kDa
-
ID gène
- 4586, 534332
-
UniProt
- P98088
Antigène
-