PARVG anticorps

N° du produit ABIN7861900

Cet anticorps anti-PARVG Monoclonal Souris (Clone 8C5-2) (ABIN7861900) détecte spécifiquement PARVG dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PARVG anticorps (ABIN7861900)

Antigène: PARVG (Parvin, gamma (PARVG))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PARVG est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 8C5-2

Détail du produit anti-PARVG anticorps

Fonction: Gamma-parvin Antibody

Specificité: The parvin family, including °™-parvin, æ-parvin and Á-parvin, link integrins and associated proteins with intracellular pathways, which regulate actin cytoskeletal dynamics and cell survival. All three family members localize to focal adhesions and function in cell adhesion, spreading, motility and survival through interactions with partners, such as integrin-linked kinase (ILK), paxillin, °™-actinin and testicular kinase 1. °™-parvin is widely expressed, with highest levels detected in the skeletal muscle, heart, liver and kidney. A complex made up of °™-parvin, ILK and the LIM protein PINCH-1 is critical for cell survival in a variety of cells, including certain cancer cells, kidney podocytes and cardiac myocytes. æ-parvin links initial integrin signals to rapid actin reorganization, thereby playing a critical role in fibroblast migration. The ILK-Á-parvin complex is essential for the establishment of cell polarity required for leukocyte migration.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: GST-tagged recombinant protein corresponding to human Gamma-parvin

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur PARVG

Antigène: PARVG (Parvin, gamma (PARVG))

Autre désignation: Gamma-parvin

Sujet:

Gamma parvin, PARVG

Jurkat cells. Human tonsil or stomach.

Poids moléculaire: 37kDa

ID gène: 64098

UniProt: Q9HBI0