PCGF3 anticorps

N° du produit ABIN7864271

L’anticorps anti-PCGF3 Monoclonal Souris est utilisé pour la détection de PCGF3 dans des échantillons de Humain. Il a été validé pour IHC, IF et FACS.

Aperçu rapide pour PCGF3 anticorps (ABIN7864271)

Antigène: PCGF3 (Polycomb Group Ring Finger 3 (PCGF3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PCGF3 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-PCGF3-1D5

Détail du produit anti-PCGF3 anticorps

Fonction: PCGF3 Antibody

Specificité: Polycomb group (PcG) proteins form multiprotein complexes that regulate expression patterns of developmental and cell proliferation genes. Several members of the PcG contain ring finger domains and are identified as a subclass of RING finger proteins. The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteinerich domain that is able to bind two zinc atoms. Proteins that contain the RING-type zinc finger conserved domain are generally involved in the ubiquitination pathway of protein degradation. PCGF3 (polycomb group ring finger 3), also known as RNF3, DONG1 or RNF3A, is a 242 amino acid transcriptional regulator that is encoded by a gene located on human chromosome 4, which encodes nearly 6 % of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. PCGF3 exists as two isoforms produced by alternative splicing events.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human PCGF3 protein

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur PCGF3

Antigène: PCGF3 (Polycomb Group Ring Finger 3 (PCGF3))

Autre désignation: PCGF3

Sujet:

DONG1, PCGF3, PCGF3_HUMAN, Polycomb group ring finger 3, Polycomb group RING finger protein 3, Ring finger protein 3, RING finger protein 3A, RNF3A

HeLa or MCF-7 cells. Human brain|testis or smooth muscle.

Poids moléculaire: 28.12Da

ID gène: 10336, 731755

UniProt: Q3KNV8

Pathways: Chromatin Binding