PCGF3 anticorps
Aperçu rapide pour PCGF3 anticorps (ABIN7861936)
Antigène
Voir toutes PCGF3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Fonction
- PCGF3 Antibody
-
Specificité
- Polycomb group (PcG) proteins form multiprotein complexes that regulate expression patterns of developmental and cell proliferation genes. Several members of the PcG contain ring finger domains and are identified as a subclass of RING finger proteins. The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteinerich domain that is able to bind two zinc atoms. Proteins that contain the RING-type zinc finger conserved domain are generally involved in the ubiquitination pathway of protein degradation. PCGF3 (polycomb group ring finger 3), also known as RNF3, DONG1 or RNF3A, is a 242 amino acid transcriptional regulator that is encoded by a gene located on human chromosome 4, which encodes nearly 6 % of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. PCGF3 exists as two isoforms produced by alternative splicing events.
-
Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
-
Immunogène
- Recombinant full-length human PCGF3 protein
-
Isotype
- IgG2b
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 1.0 mg/mL
-
Buffer
- Prepared in 10 mM PBS
-
Agent conservateur
- Azide free
-
Stock
- -20 °C,-80 °C
-
Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
-
- PCGF3 (Polycomb Group Ring Finger 3 (PCGF3))
-
Autre désignation
- PCGF3
-
Sujet
-
DONG1, PCGF3, PCGF3_HUMAN, Polycomb group ring finger 3, Polycomb group RING finger protein 3, Ring finger protein 3, RING finger protein 3A, RNF3A
HeLa or MCF-7 cells. Human brain|testis or smooth muscle.
-
Poids moléculaire
- 28.12Da
-
ID gène
- 10336, 731755
-
UniProt
- Q3KNV8
-
Pathways
- Chromatin Binding
Antigène
-