Recombinant Stathmin 1 anticorps
Aperçu rapide pour Recombinant Stathmin 1 anticorps (ABIN7862119)
Antigène
Voir toutes Stathmin 1 (STMN1) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Recombinant Stathmin 1 / STMN1 Antibody
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Specificité
- Op18 (for oncoprotein 18, also designated stathmin, prosolin or metablastin) is a conserved, Tubulin-associated, intracellular phosphoprotein. Many different phosphorylated forms of Op18 are observed, and it is expressed as two different isoforms. Op18 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phophorylation, for a variety of cell signaling pathways and is involved in both mitosis and differentiation.Op18 is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant fragment of human STMN1 protein (exact sequence is proprietary)
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Isotype
- IgG, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- Stathmin 1 (STMN1)
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Autre désignation
- Stathmin 1
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Sujet
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C1orf215, Lag, LAP18, Leukemia associated phosphoprotein p18, Metablastin, Oncoprotein 18, Op18, Phosphoprotein 19, Phosphoprotein p19, pp17, pp19, Pr22 protein, Prosolin, Protein Pr22, SMN, Stathmin1, STMN 1
Human brain or melanoma tissue. A431, Jurkat, PC3.
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Poids moléculaire
- 19kDa
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ID gène
- 3925, 209983
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UniProt
- P16949
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Pathways
- Signalisation MAPK, Dynamique des Microtubules
Antigène
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