Recombinant SDHB anticorps

N° du produit ABIN7862132

Cet anticorps Lapin Monoclonal détecte spécifiquement SDHB dans WB et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant SDHB anticorps (ABIN7862132)

Antigène: SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp SDHB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: SDHB-8974R

Détail du produit anti-SDHB anticorps

Fonction: Recombinant SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker) Antibody

Specificité: Succinate dehydrogenase B (SDHB) is an iron-sulfur subunit of mitochondrial complex II, a key component of the citric acid cycle and the electron transport chain, a respiratory complex that catalyzes the oxidation of succinate in the mitochondrial membrane.Many cancers are generally positive for SDHB, including renal cell carcinomas and gastrointestinal stromal tumors. A subset of RCC and GIST tumors that are associated with SDH mutations, Carney-Stratakis Syndrome or Carney Triad exhibit a loss of SDHB expression.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Synthetic peptide corresponding to residues in human SDHB was used as an immunogen.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur SDHB

Antigène: SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))

Autre désignation: SDHB

Sujet:

CWS2, DHSB, Iron-sulfur subunit of complex II, PGL4, SDH2, SDHB, SDHIP, Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial, Succinate Dehydrogenase Complex Subunit B Iron Sulfur Protein

Jurkat or HepG2 cells. Human kidney or heart tissue.

Poids moléculaire: 32kDa

ID gène: 6390, 465924

UniProt: P21912