TNC anticorps

N° du produit ABIN7862161

Cet anticorps anti-TNC Monoclonal Souris (Clone TNC-4806) (ABIN7862161) détecte spécifiquement TNC dans IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour TNC anticorps (ABIN7862161)

Antigène: TNC (Tenascin C (TNC))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TNC est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: TNC-4806

Détail du produit anti-TNC anticorps

Fonction: Tenascin C (Stromal Marker for Epithelial Malignancy) Antibody

Specificité: In Western blotting, it reacts with two bands of ~MW of 210 kDa and 300 kDa, identified as two isoforms of Tenascin C. Specificity of this MAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linked 79oΩhexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant human full-length TNC protein

Isotype: IgG2c, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur TNC

Antigène: TNC (Tenascin C (TNC))

Autre désignation: Tenascin C

Sujet:

Cytotactin, Glioma-associated-extracellular matrix antigen, GMEM, GP 150-225, Hexabrachion (HXB), JI, Myotendinous antigen, Neuronectin, TNC

and lung carcinomas. Staining of normal fibroblasts serves as internal positive control (IHC).|Extracellular matrix in tonsil and blood vessels. Stroma of many tumors such as breast|squamous cell

Poids moléculaire: 210kDa and 300kDa

ID gène: 3371, 143250

UniProt: P24821

Pathways: Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development