S100A8/A9 Complex (Calprotectin) anticorps
Aperçu rapide pour S100A8/A9 Complex (Calprotectin) anticorps (ABIN7863363)
Antigène
Voir toutes S100A8/A9 Complex (Calprotectin) (S100A8/A9) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Calprotectin / MRP14 / S100A9 / Calgranulin B Antibody
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Specificité
- Recognizes a protein of14 kDa, identified as MRP-14 (also known as Calgranulin B or S100AA9). It comprises 60 % of the cytoplasmic protein fraction of circulating polymorphonuclear granulocytes and is also found in monocytes, macrophages and ileal tissue eosinophils. Peripheral blood monocytes carry the antigen extra- and intracellularly, neutrophils only intracellularly. It is a potent chemotactic factor for neutrophils. Plasma concentrations are elevated in diseases associated with increased neutrophil activity, like inflammatory bowel disease. Granulocytes terminate their existence after transmigration through the intestinal wall. Therefore, it is also detectable in feces. Elevated levels have been observed in body fluids such as plasma, saliva, gingival crevicular fluid, stools, and synovial fluid during infection and inflammatory conditions. This MAb reacts with neutrophils, monocytes, and macrophages, and has been shown as an important marker for identifying macrophages in tissue sections.
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Purification
- 200ug/ml of Ab Purified from Bioreactor Concentrate.
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Immunogène
- Recombinant human MRP14 protein
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Isotype
- IgM, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- S100A8/A9 Complex (Calprotectin) (S100A8/A9) (Calprotectin (S100A8/A9))
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Autre désignation
- Calprotectin
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Sujet
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S100-A9, MRP14, calgranulin-B, calprotectin L1H subunit, leukocyte L1 complex heavy chain, migration inhibitory factor-related protein 14, S100 calcium-binding protein A9 (calgranulin B)
lymph node, or spleen, Tonsil
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Poids moléculaire
- 14kDa
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ID gène
- 6280
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UniProt
- P06702
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Pathways
- S100 Proteins
Antigène
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