Recombinant Cytokeratin 5 anticorps (AA 316-590)

N° du produit ABIN7865506

L’anticorps anti-Cytokeratin 5 Monoclonal Souris est utilisé pour la détection de Cytokeratin 5 dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour Recombinant Cytokeratin 5 anticorps (AA 316-590) (ABIN7865506)

Antigène: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cytokeratin 5 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: MSVA-605M

Détail du produit anti-Cytokeratin 5 anticorps

Épitope: AA 316-590

Expression System: CHO Cells

Fonction: Recombinant Cytokeratin 5 (KRT5) (Basal, Myoepithelial &, Mesothelial Cell Marker) Antibody

Specificité: This Mab recognizes a protein of 58 kDa, which is identified as Cytokeratin 5 (KRT5). This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Antibodies to KRT5 identify basal cells of squamous and glandular epithelia, yoepithelial, and mesothelium.Anti-cytokeratin 5 has been reported useful in the differential diagnosis of metastatic carcinoma in the pleura versus epithelioid mesothelioma. Almost all squamous cell carcinomas, half of transitional carcinomas, and many undifferentiated large cell carcinomas express.Anti-KRT5, along with anti-p63, affords a high sensitivity and specificity for squamous differentiation. Myoepithelial cells of the breast, glandular epithelia, and basal cells of the prostate are labeled with anti-KRT5.

Purification: Ab produced in CHO cell mammalian-based expression system.

Immunogène: Recombinant fragment (around aa 316-590) of human Cytokeratin 5 (KRT5) protein (exact sequence is proprietary)

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide store at 2 to 8 °C. Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Cytokeratin 5

Antigène: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Autre désignation: Cytokeratin 5

Sujet:

58 kDa Cytokeratin, DDD1, Epidermolysis Bullosa Simplex 2 (EBS2), Keratin 5, Keratin, Type II Cytoskeletal 5, Keratin-5, Type-II Cytoskeletal 5, Type-II keratin Kb5

Tonsil: A moderate to strong cytoplasmic KRT5 staining should be seen in virtually all squamous epithelial cells. Prostate: A strong cytoplasmic staining should be present in the majority of basal cells.

Poids moléculaire: 58kDa

ID gène: 3852, 433845

UniProt: P13647