Recombinant Elastin anticorps

N° du produit ABIN7865516

Cet anticorps anti-Elastin Monoclonal Lapin (Clone MSVA-648R) (ABIN7865516) détecte spécifiquement Elastin dans IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant Elastin anticorps (ABIN7865516)

Antigène: Elastin (ELN)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Elastin est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: MSVA-648R

Détail du produit anti-Elastin anticorps

Expression System: HEK-293 Cells

Fonction: Recombinant Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis) Antibody

Specificité: Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries.It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticityto the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.

Purification: Ab produced in HEK293 cell mammalian-based expression system.

Immunogène: Recombinant full-length human Elastin protein

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Elastin

Antigène: Elastin (ELN)

Autre désignation: Elastin

Sujet:

Elastin, ELN, SVAS, Tropoelastin, WBS, WS

Colon: A moderate to strong elastin immunostaining should be seen of fibres in the lamina propria, around smooth muscle cells of the muscularis mucosae, and in blood vessels (subendothelial).

Poids moléculaire: 70kDa

ID gène: 2006, 647061

UniProt: P15502

Pathways: Regulation of Actin Filament Polymerization