CALB1 anticorps (AA 7-96)

N° du produit ABIN7865499

Cet anticorps Souris Monoclonal détecte spécifiquement CALB1 dans IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CALB1 anticorps (AA 7-96) (ABIN7865499)

Antigène: CALB1 (Calbindin (CALB1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CALB1 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: MSVA-471M

Détail du produit anti-CALB1 anticorps

Épitope: AA 7-96

Fonction: Calbindin 1 (CALB1) Antibody

Specificité: The family of EF-hand type Ca2+-binding proteins includes Calbindin D28K, Calbindin D9K, S-100 (also designated oncomodulin). Calbindin D28K, also known as calbindin, CALB1, D-28K or vitamin D-dependent calcium-binding protein, is a 261-amino acid protein with 6 EF-hand domains, 4 of which are active calcium-binding domains. Expressed in brain, ovary, uterus, testis, pancreas, liver, kidney and intestine, Calbindin D28K acts as a calcium-buffering agent and alters the activity of the plasma membrane ATPase. In neuronal cells, Calbindin D28K modulates calcium channel activity, calcium transients and intrinsic neuronal firing activity. Also, Calbindin D28K has been implicated to play a role in apoptosis and microtubule function.

Purification: Ab purified from Bioreactor Concentrate by Protein A.

Immunogène: Recombinant fragment (around aa 7-96) of human CALB1 protein (exact sequence is proprietary)

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur CALB1

Antigène: CALB1 (Calbindin (CALB1))

Autre désignation: Calbindin 1

Sujet:

avian-type, CAB27, CALB 1, CALB, CALB1, CALB1_HUMAN, Calbindin 1 28 kDa, Calbindin, Calbindin D28, D 28K, D-28K, D28K, OTTHUMP00000166027, OTTHUMP00000225441, RTVL H protein, Vitamin D dependent calcium binding protein, Vitamin D dependent calcium binding protein avian type, Vitamin D-dependent calcium-binding protein

Kidney: A subset of the cells of distal tubuli should show an intense cytoplasmic calbindin 1 immunostaining.

Poids moléculaire: 52kDa

ID gène: 793, 65425

UniProt: P05937