CBX3 anticorps (pSer93) (HRP)

N° du produit ABIN743087

L’anticorps Lapin Polyclonal anti-CBX3 a été validé pour ELISA, IHC (p) et IHC (fro). Il convient pour détecter CBX3 dans des échantillons de Humain.

Aperçu rapide pour CBX3 anticorps (pSer93) (HRP) (ABIN743087)

Antigène: CBX3 (Chromobox Homolog 3 (CBX3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CBX3 est conjugé à/à la HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-CBX3 anticorps (HRP)

Épitope: pSer93

Homologie: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human HP1 gamma around the phosphorylation site of Ser83

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CBX3

Antigène: CBX3 (Chromobox Homolog 3 (CBX3))

Autre désignation: HP1 gamma

Sujet:

Synonyms: HP1 gamma phospho S93, HP1 gamma phospho Ser93, p-HP1 gamma Ser93, CBX 3, CBX3, Chromobox homolog 3, Chromobox protein homolog 3, HECH, Heterochromatin like protein 1, Heterochromatin protein 1 homolog gamma, Heterochromatin protein HP1 gamma, HP1 gamma homolog, HP1Hs gamma , Modier 2, protein HP1-GAMMA, HP1g, M32, HP1 gamma, MGC118084, CBX3_HUMAN, Modier 2 protein.

Background: HP1 gamma appears to be involved in transcriptional silencing in heterochromatin-like complexes. It recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. HP1 gamma may contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR) and involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

ID gène: 11335