CD59 anticorps

N° du produit ABIN7865599

Cet anticorps anti-CD59 Monoclonal Souris (Clone Bra10G) (ABIN7865599) détecte spécifiquement CD59 dans IHC, FACS, IF et ICC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CD59 anticorps (ABIN7865599)

Antigène: CD59

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD59 est non-conjugé

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: Bra10G

Détail du produit anti-CD59 anticorps

Fonction: anti-CD59 mouse monoclonal, Bra10G, purified

Purification: affinity chromatography

Immunogène: K-562 leukemia cells

Isotype: IgG2b kappa

Information d'application

Indications d'application:

ICC/IF_dilution: 1:100-1:200 (0.5-1.0 μg/mL)

FACS_dilution: 0.5-1.0 μg/million cells in 0.1 ml

IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS with 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: store at 2 - 8 °C

Détails sur CD59

Antigène: CD59

Autre désignation: CD59

Sujet: CD59, or protectin, is a 18-22 kDa cell surface molecule on a GPI anchor. It regulates complement-mediated cell lysis and is supposed to protect normal and tumor cells from cytotoxic attack by homologous complement through binding to C8 and C9. CD59 is expressed on leukocytes, vascular epithelium, a variety of epithelial cells and placenta. B-cells express low levels. The expression of CD59 on erythrocytes is important for their survival. Genetic defects in GPI-anchor attachment, that cause a reduction or loss of CD59 and CD55 on erythrocytes produce the symptoms of the disease Paroxysmal nocturnal hemoglobinuria (PNH). Bra10G was typed at the VIth International Workshop on human leucocyte differentiation antigens. Positive control: Daudi, CEM, K562, HPB.ALL, Jurkat, Raji, human lymphocytes, human lymph node and tonsil.

Pathways: Système du Complément