IFNA2 anticorps

N° du produit ABIN7865671

Cet anticorps anti-IFNA2 Monoclonal Souris (Clone N27) (ABIN7865671) détecte spécifiquement IFNA2 dans ELISA, WB et IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour IFNA2 anticorps (ABIN7865671)

Antigène: IFNA2 (Interferon, alpha 2 (IFNA2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IFNA2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Clone: N27

Détail du produit anti-IFNA2 anticorps

Fonction: anti-Interferon α 2 mouse monoclonal, N27, purified

Purification: affinity chromatography

Immunogène: E.coli derived recombinant human IFNalpha2c

Isotype: IgG1 kappa

Information d'application

Indications d'application:

WB_dilution: 1:50-1:100 (1-2 μg/mL)

IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)

elisa_dilution: assay dependent

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS with 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: store at 2 - 8 °C

Détails sur IFNA2

Antigène: IFNA2 (Interferon, alpha 2 (IFNA2))

Autre désignation: Interferon alpha 2

Sujet: The alpha interferons are involved in virus resistance in target cells for these viruses. They are known to block cell proliferation and to regulate MHC class I antigen expression. The IFNα family has over 20 genes and pseudogenes in two families (I and II), one with a mature length of 166aa and one of 172aa. Cells producing IFNα are lymphocytes, monocytes, macrophages and cell lines such as Namalwa and KGI. Bioassays for IFNα include cytopathic effect blocking, by viruses such as VSV, SFV and BMCV, on their target cells. A number of receptors for IFNα are now known and seem to be expressed on most cell types. N27 is specific for human IFNα2 and does not cross react with human IFNα1. N27 reacts with linear peptide 43aa-53aa, placing the epitope outside the immunodominant regions I and II. Positive control: Human IFNα2, Namalwa and KGI cells. Pair: N39

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Hepatitis C