Progesterone Receptor anticorps

N° du produit ABIN7865720

Cet anticorps Souris Monoclonal détecte spécifiquement Progesterone Receptor dans IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Progesterone Receptor anticorps (ABIN7865720)

Antigène: Progesterone Receptor (PGR)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Progesterone Receptor est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: PR-80

Détail du produit anti-Progesterone Receptor anticorps

Fonction: anti-Progesterone Receptor mouse monoclonal, PR-80, purified

Purification: affinity chromatography

Immunogène: recombinant human progesterone receptor protein

Isotype: IgG1 kappa

Information d'application

Indications d'application:

IHC-paraffin_dilution: 1:25-1:50 (2-4 μg/mL, microwave treatment in 10 mM citrate buffer pH 6.0 recommended)

IHC-frozen_dilution: 1:25-1:50 (2-4 μg/mL)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS with 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: store at 2 - 8 °C

Détails sur Progesterone Receptor

Antigène: Progesterone Receptor (PGR)

Autre désignation: Progesterone Receptor

Sujet: PR-80 is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81 kDa) and PR-B (116 kDa). Expression of PgR has been suggested to reflect an intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone. Positive control: PR positive breast cancer, T47-D cells.

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration