Thyroglobulin anticorps
Aperçu rapide pour Thyroglobulin anticorps (ABIN7865744)
Antigène
Voir toutes Thyroglobulin (TG) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- anti-Thyroglobulin mouse monoclonal, EBS-O-170, purified
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Purification
- affinity chromatography
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Immunogène
- human thyroglobulin
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Isotype
- IgG1 kappa
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Indications d'application
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ICC/IF_dilution: 1:100-1:200 (0.5-1.0 μg/mL)
FACS_dilution: 0.5-1.0 μg/million cells in 0.1 ml
IHC-paraffin_dilution: 1:50-1:100 (1-2 μg/mL, microwave treatment in 10 mM citrate buffer pH 6.0 recommended)
WB_dilution: 1:100-1:200 (0.5-1 μg/mL)
IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)
elisa_dilution: assay dependent
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 100 μg/mL
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Buffer
- PBS with 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- store at 2 - 8 °C
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- Thyroglobulin (TG)
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Autre désignation
- Thyroglobulin
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Sujet
- EBS-O-170 reacts with thyroglobulin, a 660 kDa dimeric pre-protein with multiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. The vast majority of follicular carcinomas of the thyroid are positive for thyroglobulin even though sometimes only focally. Poorly differentiated thyroid carcinomas are frequently thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. EBS-O-170 has a high affinity for thyroglobulin (Ka = 8.6 x 10^-9). Positive control: Human thyroid.
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Pathways
- Thyroid Hormone Synthesis
Antigène
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