VCAM1 anticorps

N° du produit ABIN7865753

Cet anticorps Souris Monoclonal détecte spécifiquement VCAM1 dans FACS, IHC, ICC, ELISA et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour VCAM1 anticorps (ABIN7865753)

Antigène: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp VCAM1 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC), ELISA, Immunofluorescence (IF)

Clone: B-K9

Détail du produit anti-VCAM1 anticorps

Fonction: anti-CD106 mouse monoclonal, B-K9, purified

Purification: affinity chromatography

Immunogène: activated umbilical cord vein endothelial cells (HUVEC)

Isotype: IgG1 kappa

Information d'application

Indications d'application:

ICC/IF_dilution: 1:100-1:200 (0.5-1.0 μg/mL)

FACS_dilution: 0.5-1.0 μg/million cells in 0.1 ml

IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)

elisa_dilution: assay dependent

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS with 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: store at 2 - 8 °C

Détails sur VCAM1

Antigène: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Autre désignation: CD106

Sujet: CD106 is a protein of 110 kDa, also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100. CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. In addition, epithelial cells and cancers cells can be positive, like in kidney and prostate cancer. CD106 serves as a ligand for leukocytes integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses. B-K9 inhibits the binding of leukocytes to VCAM-1 on stimulated endothelial cells. Positive control: Human placenta or tonsil, kidney, some prostate cancers.

Pathways: Carbohydrate Homeostasis