beta Amyloid anticorps (AA 1-100, AA 8-16)

N° du produit ABIN7867901

Cet anticorps Souris Monoclonal détecte spécifiquement beta Amyloid dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour beta Amyloid anticorps (AA 1-100, AA 8-16) (ABIN7867901)

Antigène: beta Amyloid (Abeta) (Amyloid beta (Abeta))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp beta Amyloid est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: APP-4469

Détail du produit anti-beta Amyloid anticorps

Épitope: AA 1-100, AA 8-16

Fonction: Beta Amyloid Antibody / APP (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: A portion of amino acids 1-100 of the amyloid beta protein was used as the immunogen for the Beta Amyloid antibody. This antibody recognizes an epitope in the region of amino acids 8-16 of the amyloid precursor protein.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Beta Amyloid antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the Beta Amyloid antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur beta Amyloid

Antigène: beta Amyloid (Abeta) (Amyloid beta (Abeta))

Autre désignation: Beta Amyloid

Sujet: Proteolytic cleavage of the Amyloid protein precursor (APP) gives rise to the b-Amyloid and Amyloid A4 proteins, which are present in human platelets. Amyloid deposition is associated with type II diabetes, Down syndrome and a variety of neurological disorders, including Alzheimer s disease. The Amyloid precursor protein (APP) undergoes alternative splicing, resulting in several isoforms. Proteolytic cleavage of APP leads to the formation of the 4 kDa Amyloid b/A4 Amyloid protein. This protein is involved in the formation of neurofibrillary tangles and plaques that characterize the senile plaques of Alzheimer s patients. APLP1 (Amyloid precursor-like protein 1) and APLP2 are structurally similar to APP. Human APLP2 is a membrane-bound sperm protein that contains a region highly homologous to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer s disease patients.

UniProt: P05067

Pathways: Inflammasome