FABP1 anticorps (AA 1-127)

N° du produit ABIN7868051

Cet anticorps Souris Monoclonal détecte spécifiquement FABP1 dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour FABP1 anticorps (AA 1-127) (ABIN7868051)

Antigène: FABP1 (Fatty Acid Binding Protein 1, Liver (FABP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FABP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: FABP1-4462

Détail du produit anti-FABP1 anticorps

Épitope: AA 1-127

Fonction: FABP1 Antibody / Fatty Acid Binding Protein 1

Purification: Protein A/G affinity

Immunogène: A human recombinant FABP1 protein fragment (within amino acids 1-127) was used as the immunogen for the FABP1 antibody.

Isotype: IgG2, kappa

Information d'application

Indications d'application: Optimal dilution of the FABP1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the FABP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur FABP1

Antigène: FABP1 (Fatty Acid Binding Protein 1, Liver (FABP1))

Autre désignation: FABP1

Sujet: Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epithelium (E-FABP, psoriasis-associated FABP, PA-FABP), striated muscle and heart (H-FABP, mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP or FABP1), myelin (M-FABP) and testis (T-FABP). FABP1 (L-FABP) expression is modulated by developmental, hormonal, dietary and pharmacological factors, and is required for cholesterol synthesis and metabolism.

UniProt: P07148

Pathways: Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha