OLIG2 anticorps (AA 1-141)

N° du produit ABIN7868142

L’anticorps anti-OLIG2 Monoclonal Souris est utilisé pour la détection de OLIG2 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour OLIG2 anticorps (AA 1-141) (ABIN7868142)

Antigène: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp OLIG2 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: ODTF2-1

Détail du produit anti-OLIG2 anticorps

Épitope: AA 1-141

Fonction: OLIG2 Antibody

Purification: Protein G affinity

Immunogène: A portion of amino acids 1-141 from the human protein was used as the immunogen for this OLIG2 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the OLIG2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the OLIG2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur OLIG2

Antigène: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Autre désignation: OLIG2

Sujet: Olig2, a basic helix-loop-helix transcription factor, is involved in oligodendroglial specification. Olig2 expression has been reported in most glial tumors, such as oligodendrogliomas and astrocytomas. Although more than half of glioblastomas are positive for Olig2, expression is very weak in terms of both percentage of labeled cells and intensity. No Olig2 expression has been found in the non-glial tumors including neuro-epithelial tumors, ependymomas, sub-ependymomas, medulloblastomas, and non-neuroepithelial tumors, such as CNS lymphomas, meningiomas, schwannomas, atypical teratoid / rhabdoid tumor, and haemangioblastomas. Compared to the strong staining seen in glioma samples, a weak expression is observed in non-tumoral brain tissue (gliosis).

UniProt: Q13516