Recombinant Iba1 anticorps (AA 1-146)

N° du produit ABIN7868160

L’anticorps anti-Iba1 Monoclonal Lapin est utilisé pour la détection de Iba1 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Recombinant Iba1 anticorps (AA 1-146) (ABIN7868160)

Antigène: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Iba1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: AIF1-8970R

Détail du produit anti-Iba1 anticorps

Épitope: AA 1-146

Fonction: Allograft inflammatory factor 1 Antibody / AIF1 / IBA1 (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 1-146) from the human protein was used as the immunogen for the Allograft inflammatory factor 1 antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the Allograft inflammatory factor 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the Allograft inflammatory factor 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Iba1

Antigène: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Autre désignation: Allograft inflammatory factor 1

Sujet: AIF1 is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).

UniProt: P55008

Pathways: Smooth Muscle Cell Migration