Iba1 anticorps (AA 1-146)

N° du produit ABIN7868167

Cet anticorps anti-Iba1 Monoclonal Souris (Clone AIF1-2493) (ABIN7868167) détecte spécifiquement Iba1 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Iba1 anticorps (AA 1-146) (ABIN7868167)

Antigène: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Iba1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: AIF1-2493

Détail du produit anti-Iba1 anticorps

Épitope: AA 1-146

Fonction: AIF1 Antibody / IBA1

Purification: Protein G affinity chromatography

Immunogène: A portion of amino acids 1-146 from the human protein was used as the immunogen for the AIF1 antibody.

Isotype: IgG2c, kappa

Information d'application

Indications d'application: Titering of the AIF1 antibody may be required for optimal performance.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the AIF1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Iba1

Antigène: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Autre désignation: AIF1

Sujet: AIF1 (Allograft inflammatory factor 1), also called IBA1 (Ionized calcium-binding adapter molecule 1) is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1/IBA1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, it colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding the protein resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).

UniProt: P55008

Pathways: Smooth Muscle Cell Migration