CDC5L anticorps (AA 1-148)

N° du produit ABIN7868175

L’anticorps anti-CDC5L Monoclonal Souris est utilisé pour la détection de CDC5L dans des échantillons de Humain. Il a été validé pour FACS et IHC (p).

Aperçu rapide pour CDC5L anticorps (AA 1-148) (ABIN7868175)

Antigène: CDC5L (CDC5 Cell Division Cycle 5-Like (S. Pombe) (CDC5L))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CDC5L est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: PCRP-CDC5L-2C6

Détail du produit anti-CDC5L anticorps

Épitope: AA 1-148

Fonction: CDC5L Antibody / Cell division cycle 5-like protein

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 1-148) from the human protein was used as the immunogen for the CDC5L antibody.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal dilution of the CDC5L antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the CDC5L antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur CDC5L

Antigène: CDC5L (CDC5 Cell Division Cycle 5-Like (S. Pombe) (CDC5L))

Autre désignation: CDC5L

Sujet: Cdc5L (cell division cycle 5-like protein, pombe Cdc5-related protein) is a DNA-binding protein encoded by the human gene CDC5L. Cdc5L contains two HTH Myb-type DNA-binding domains and may shuttle between cytoplasm and nucleus. It is involved in cell cycle control and may act as a transcription activator. Cdc5L is a spliceosomal protein that is highly conserved across species. It belongs to the group of proteins that comprise the core of spliceosomal complexes and are essential for pre-mRNA splicing. Cdc5L is involved in the second catalytic step of pre-mRNA splicing, which involves cleavage at the 3' splice site and the ligation of the exons. This process releases the intact intron lariat. A chromosomal aberration involving Cdc5L is found in multicystic renal dysplasia. This aberration is caused by a translocation (t 6,19,p21,q13.1) with USF-2.

UniProt: Q99459

Pathways: Activation of Innate immune Response, Chromatin Binding