SIGMAR1 anticorps (AA 1-154)

N° du produit ABIN7868213

Cet anticorps Lapin Polyclonal détecte spécifiquement SIGMAR1 dans WB, ELISA et IHC (p). Il présente une réactivité avec des échantillons de Humain, Souris, Rat et Singe.

Aperçu rapide pour SIGMAR1 anticorps (AA 1-154) (ABIN7868213)

Antigène: SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIGMAR1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-SIGMAR1 anticorps

Épitope: AA 1-154

Fonction: Sigma1-receptor Antibody / SIGMAR1

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids G1-H154) was used as the immunogen for the Sigma1-receptor antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Sigma1-receptor antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Sigma1-receptor antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur SIGMAR1

Antigène: SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))

Autre désignation: Sigma1-receptor

Sujet: The sigma-1 receptor, one of two sigma receptor subtypes, is a chaperone protein at the endoplasmic reticulum (ER) that modulates calcium signaling through the IP3 receptor. In humans, the sigma-1 receptor is encoded by the SIGMAR1 gene. This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor, it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.

UniProt: Q99720

Pathways: SARS-CoV-2 Protein Interactome