Glutaredoxin 2 anticorps (AA 1-164)

N° du produit ABIN7868229

L’anticorps anti-Glutaredoxin 2 Polyclonal Lapin est utilisé pour la détection de Glutaredoxin 2 dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA, IHC (p) et IF.

Aperçu rapide pour Glutaredoxin 2 anticorps (AA 1-164) (ABIN7868229)

Antigène: Glutaredoxin 2 (GRX2)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glutaredoxin 2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-Glutaredoxin 2 anticorps

Épitope: AA 1-164

Fonction: GLRX2 Antibody / Glutaredoxin 2

Purification: Affinity purified

Immunogène: A human recombinant partial protein (amino acids M1-Q164) was used as the immunogen for the GLRX2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the GLRX2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the GLRX2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Glutaredoxin 2

Antigène: Glutaredoxin 2 (GRX2)

Autre désignation: GLRX2

Sujet: GLRX2 (Glutaredoxin-2) also known as Glutaredoxin-2, mitochondrial or GRX2, is a protein that in humans is encoded by the GLRX2 gene. Glutaredoxins(e.g., GLRX) are a family of glutathione-dependent hydrogen donors that participate in a variety of cellular redox reactions. By sequence analysis, Lundberg et al.(2001) and Gladyshev et al.(2001) identified the GLRX2 gene within a clone mapping to chromosome 1q31.2-q31.3. Lundberg et al.(2001) determined that the GLRX2 gene contains 5 exons spanning about 9.6 kb. The GLRX2B transcript uses a first exon(exon 1B) located upstream from the first exon used by the GLRX2A transcript(exon 1A), suggesting that alternative splicing generates the isoforms. Lundberg et al.(2001)assayed reductase activity in recombinant proteins of both GLRX2 isoforms. They found that both have GSH-dependent dehydroascorbate reductase activity and 2-hydroxyethyl disulfide reductase activity.

UniProt: Q9NS18

Pathways: Cell RedoxHomeostasis