CRYAA anticorps (AA 1-173)

N° du produit ABIN7868251

Cet anticorps anti-CRYAA Monoclonal Souris (Clone 8H6) (ABIN7868251) détecte spécifiquement CRYAA dans WB et FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CRYAA anticorps (AA 1-173) (ABIN7868251)

Antigène: CRYAA (Crystallin, alpha A (CRYAA))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CRYAA est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: 8H6

Détail du produit anti-CRYAA anticorps

Épitope: AA 1-173

Fonction: CRYAA Antibody / Alpha A Crystallin

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids M1-S173) was used as the immunogen for the CRYAA antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the CRYAA antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the CRYAA antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur CRYAA

Antigène: CRYAA (Crystallin, alpha A (CRYAA))

Autre désignation: CRYAA

Sujet: Alpha-crystallin A chain is a protein that in humans is encoded by the CRYAA gene. Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, instead they hold them in large soluble aggregates. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Alpha-A and alpha-B gene products are differentially expressed, alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Defects in this gene cause autosomal dominant congenital cataract (ADCC).

UniProt: P02489

Pathways: M Phase