NUMA1 anticorps (AA 1-1954)
Aperçu rapide pour NUMA1 anticorps (AA 1-1954) (ABIN7868351)
Antigène
Voir toutes NUMA1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-1954
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Fonction
- NUMA1 Antibody / Nuclear mitotic apparatus protein 1
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Purification
- Antigen affinity purified
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Immunogène
- An E.coli-derived human recombinant protein (M1-E1954) was used as the immunogen for the NUMA1 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the NUMA1 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the NUMA1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
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Autre désignation
- NUMA1
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Sujet
- Nuclear mitotic apparatus protein 1 is a protein that in humans is encoded by the NUMA1 gene. This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants.
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UniProt
- Q14980
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Pathways
- Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, M Phase
Antigène
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