Recombinant CXCR5 anticorps (AA 1-200)

N° du produit ABIN7868449

Cet anticorps anti-CXCR5 Monoclonal Lapin (Clone CXCR5-8279R) (ABIN7868449) détecte spécifiquement CXCR5 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant CXCR5 anticorps (AA 1-200) (ABIN7868449)

Antigène: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CXCR5 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CXCR5-8279R

Détail du produit anti-CXCR5 anticorps

Épitope: AA 1-200

Fonction: CD185 Antibody / CXCR5 / BLR1 / MDR15

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the CD185 antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the CD185 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the CD185 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur CXCR5

Antigène: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Autre désignation: CD185

Sujet: Burkitt s lymphoma receptor 1 (Blr1), also called CD185, CXCR5 and MDR15, is a lymphocyte specific chemokine receptor expressed at low levels in secondary lymphoid tissues and in defined structures of the cerebellum. The G protein-coupled receptor has significant homology to other chemokine receptors. Stimulation of Blr1 by its ligand, B-lymphocyte chemoattractant (BLC) results in an influx of calcium into the cell and the chemotaxis of the cell. Blr1 is required for B-cell migration into splenic and Peyer s patch follicles. BLC expression in Peyer s patches is highest in germinal centers, where B cells undergo somatic mutation and affinity maturation.

UniProt: P32302