GCET2 anticorps (AA 1-200)

N° du produit ABIN7868493

L’anticorps anti-GCET2 Monoclonal Souris est utilisé pour la détection de GCET2 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour GCET2 anticorps (AA 1-200) (ABIN7868493)

Antigène: GCET2 (Germinal Center Expressed Transcript 2 (GCET2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GCET2 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: HGAL-830

Détail du produit anti-GCET2 anticorps

Épitope: AA 1-200

Fonction: HGAL Antibody / GCSAM / GCET2

Purification: Protein A/G affinity

Immunogène: A portion of amino acids 1-200 was used as the immunogen for the HGAL antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the HGAL antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the HGAL antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur GCET2

Antigène: GCET2 (Germinal Center Expressed Transcript 2 (GCET2))

Autre désignation: HGAL

Sujet: Germinal center-associated signaling and motility protein / GCSAM, also called GCET2 and HGAL or hGAL, contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4. HGAL is specifically expressed in germinal center B-cells, but is absent in mantle and marginal zone B-cells and in the inter-follicular and para-cortical regions in normal tonsils and lymph nodes. Its high degree of specificity for germinal center B-cells makes anti-HGAL an ideal marker for the detection of germinal center-derived B-cell lymphomas. HGAL expression has been used to help elucidate nodal marginal zone lymphoma (NMZL) from cases of diffuse follicle center lymphoma. Additionally, HGAL expression was shown to correlate with survival in patients with diffuse large B-cell lymphoma (DLBCL).

UniProt: Q8N6F7