GCET2 anticorps (AA 1-200)

N° du produit ABIN7868494

Cet anticorps anti-GCET2 Monoclonal Souris (Clone HGAL-2834) (ABIN7868494) détecte spécifiquement GCET2 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour GCET2 anticorps (AA 1-200) (ABIN7868494)

Antigène: GCET2 (Germinal Center Expressed Transcript 2 (GCET2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GCET2 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: HGAL-2834

Détail du produit anti-GCET2 anticorps

Épitope: AA 1-200

Fonction: GCSAM Antibody / HGAL (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the GCSAM antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the GCSAM antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the GCSAM antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur GCET2

Antigène: GCET2 (Germinal Center Expressed Transcript 2 (GCET2))

Autre désignation: GCSAM

Sujet: Recognizes a protein identified as HGAL, also called GCSAM (Germinal center-associated signaling and motility protein). It contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4. HGAL is specifically expressed in germinal center B-cells, but is absent in mantle and marginal zone B-cells and in the inter-follicular and para-cortical regions in normal tonsils and lymph nodes. Its high degree of specificity for germinal center B-cells makes anti-HGAL an ideal marker for the detection of germinal center-derived B-cell lymphomas. HGAL expression has been used to help elucidate nodal marginal zone lymphoma (NMZL) from cases of diffuse follicle center lymphoma. Additionally, HGAL expression was shown to correlate with survival in patients with diffuse large B-cell lymphoma (DLBCL).

UniProt: Q8N6F7