IL20RA anticorps (AA 1-200)

N° du produit ABIN7868586

L’anticorps anti-IL20RA Monoclonal Souris est utilisé pour la détection de IL20RA dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour IL20RA anticorps (AA 1-200) (ABIN7868586)

Antigène: IL20RA (Interleukin 20 Receptor alpha (IL20RA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL20RA est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: IL20RA-0001

Détail du produit anti-IL20RA anticorps

Épitope: AA 1-200

Fonction: IL20RA Antibody / IL-20 receptor subunit alpha (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the IL20RA antibody.

Isotype: IgG2, kappa

Information d'application

Indications d'application: Optimal dilution of the IL20RA antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the IL20RA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur IL20RA

Antigène: IL20RA (Interleukin 20 Receptor alpha (IL20RA))

Autre désignation: IL20RA

Sujet: The class II cytokine receptor family includes 12 members, 11 of which combine as various heterodimers to transduce signals across the cellular membrane for 27 cytokines. These cytokines are divided into four structurally related groups: six cytokines of the IL-10 family, 17 type I IFNs, one type II IFN and three IFN-l. IL-20 is a member of the IL-10 family of cytokines that has been shown to be upregulated in psoriatic skin. The receptor for IL-20 (IL-20R) exists as a dimer consisting of IL-20Ra and IL-20Rb. IL-20R also functions as a receptor for IL-19, IL-24 and IL-26. It is highly expressed in skin, brain and testis. IL-20, IL-20Ra and IL-20Rb all have higher expression levels in psoriatic lesional (LS) skin than in nonlesional (NL) skin, suggesting a role for these proteins as potential therapeutic targets. IL-20 can induce signal transducer and activator of transcription (Stat) activation through IL-20R.

UniProt: Q9UHF4