PLK1 anticorps (AA 1-200)

N° du produit ABIN7868708

Cet anticorps Souris Monoclonal détecte spécifiquement PLK1 dans ELISA et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour PLK1 anticorps (AA 1-200) (ABIN7868708)

Antigène: PLK1 (Polo-Like Kinase 1 (PLK1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PLK1 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: PLK1-7122

Détail du produit anti-PLK1 anticorps

Épitope: AA 1-200

Fonction: Polo like kinase 1 Antibody / PLK1 (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: A recombinant fragment of human protein (within amino acids 1-200) was used as the immunogen for the Polo like kinase 1 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Polo like kinase 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the Polo like kinase 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur PLK1

Antigène: PLK1 (Polo-Like Kinase 1 (PLK1))

Autre désignation: Polo like kinase 1

Sujet: Plk (for polo-like kinase) encodes a serine/threonine kinase that is closely related to polo and CDC5, genes that are required for passage through mitosis in Drosophila and Saccharomyces, respectively. Polo and CDC5 both code for proteins that are involved in regulating the function of the mitotic spindle. Plk protein accumulates in the cell during the S and G2 phases of the cell cycle, Plk protein content and catalytic activity peak at the onset of mitosis, followed by a rapid reduction after mitosis. Plk expression is detectable in mitotically active tissues such as colon and placenta, as well as in tumors of various origins. It has also been suggested that Plk may serve as a marker of cell proliferation.

UniProt: P53350

Pathways: Cycle Cellulaire, M Phase