ILK anticorps (AA 1-203)
Aperçu rapide pour ILK anticorps (AA 1-203) (ABIN7868812)
Antigène
Voir toutes ILK AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-203
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Fonction
- Zebrafish Integrin-linked kinase Antibody / ILK
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Purification
- Antigen affinity chromatography
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Immunogène
- An E.coli-derived zebrafish Integrin-linked kinase recombinant protein (amino acids M1-H203) was used as the immunogen for the Zebrafish Integrin-linked kinase antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Optimal dilution of the Zebrafish Integrin-linked kinase antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the Zebrafish Integrin-linked kinase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- ILK (Integrin-Linked Kinase (ILK))
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Autre désignation
- Integrin-linked kinase
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Sujet
- ILK, also known as Integrin-linked kinase, is a serine-threonine protein kinase. Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK) interacts with the cytoplasmic domain of beta-1 integrin. This gene was initially described to encode a serine/ threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. Recent results showed that ILK contains 5 ankyrin-like repeats, and that the C-terminal kinase domain is actually a pseudo-kinase with adaptor function.
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UniProt
- Q6PHD6
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Pathways
- Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
Antigène
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