CDK5 anticorps (AA 1-226)

N° du produit ABIN7868863

Cet anticorps anti-CDK5 Polyclonal Lapin (ABIN7868863) détecte spécifiquement CDK5 dans WB. L’anticorps est réactif avec des échantillons de Poisson zèbre (Danio rerio).

Aperçu rapide pour CDK5 anticorps (AA 1-226) (ABIN7868863)

Antigène: CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

Reactivité: Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CDK5 anticorps

Épitope: AA 1-226

Fonction: Zebrafish Cdk5 Antibody

Purification: Antigen affinity chromatography

Immunogène: An E.coli-derived zebrafish Cdk5 recombinant protein (amino acids M1-Q226) was used as the immunogen for the Zebrafish Cdk5 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal dilution of the Zebrafish Cdk5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Zebrafish Cdk5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur CDK5

Antigène: CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

Autre désignation: Cdk5

Sujet: CDK5, Cyclin-Dependent Kinase 5, is also known as PSSALRE. The p34 (CDC2) protein kinase regulates important transitions in the eukaryotic cell cycle. The PSSALRE expression is in all human tissues and cell lines tested. The the CDK5 gene is mapped to chromosome 7q36. Cyclin-dependent kinase-5 is predominantly expressed in neurons where it phosphorylates both high molecular weight neurofilaments and microtubule-associated protein tau. CDK5 is required for proper development of the mammalian central nervous system. To be activated, CDK5 must associate with its regulatory subunit, p35 (CDK5R1). CDK5 can phosphorylate DARPP32 at threonine-75, converting it into an inhibitor of PKA.

UniProt: Q9DE44

Pathways: Cycle Cellulaire, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis