Syndecan 1 anticorps (AA 1-250)

N° du produit ABIN7868956

Cet anticorps anti-Syndecan 1 Monoclonal Souris (Clone SDC1-7177) (ABIN7868956) détecte spécifiquement Syndecan 1 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Syndecan 1 anticorps (AA 1-250) (ABIN7868956)

Antigène: Syndecan 1 (SDC1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Syndecan 1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SDC1-7177

Détail du produit anti-Syndecan 1 anticorps

Épitope: AA 1-250

Fonction: CD138 Antibody / Syndecan-1 / SDC1

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 1-250) from the human protein was used as the immunogen for the CD138 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the CD138 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the CD138 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Syndecan 1

Antigène: Syndecan 1 (SDC1)

Autre désignation: CD138

Sujet: CD138, also designated syndecan-1, is a member of the syndecan family of four transmembrane spanning proteins capable of binding to heparan sulfate and chondroitin sulfate molecules. The syndecans main functions are to control cell growth and differentiation as well as to maintain cell adhesion and cell migration. Under normal conditions CD138 is predominantly expressed on mature plasma cells and early preB-cells, while other haematolymphoid cells are negative. Various types of epithelial cells are also CD138 positive. Squamous epithelial cells show strong membranous and some cytoplasmic staining, except for the mature superficial squamous epithelial cells which are unstained. Mature mesenchymal and neural tissues are not stained. Among haematolymphoid neoplasms, CD138 is expressed in practically all cases of plasma cell malignancies. Among non-haematolymphoid neoplasms the expression of CD138 is found in various types of carcinoma.

UniProt: P18827

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism