YWHAE anticorps (AA 1-255)

N° du produit ABIN7868983

Cet anticorps anti-YWHAE Monoclonal Souris (Clone 3G11G2) (ABIN7868983) détecte spécifiquement YWHAE dans WB, IF, IHC (p) et FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour YWHAE anticorps (AA 1-255) (ABIN7868983)

Antigène: YWHAE (14-3-3 epsilon (YWHAE))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp YWHAE est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: 3G11G2

Détail du produit anti-YWHAE anticorps

Épitope: AA 1-255

Fonction: YWHAE Antibody / 14-3-3 epsilon

Purification: Antigen affinity purified

Immunogène: Recombinant human YWHAE protein (amino acids M1-Q255) was used as the immunogen for the YWHAE antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the YWHAE antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the YWHAE antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur YWHAE

Antigène: YWHAE (14-3-3 epsilon (YWHAE))

Autre désignation: YWHAE

Sujet: 14-3-3 protein epsilon is a protein that in humans is encoded by the YWHAE gene. This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100 % identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene.

UniProt: P62258

Pathways: Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase