TARDBP anticorps (AA 1-264)
Aperçu rapide pour TARDBP anticorps (AA 1-264) (ABIN7869002)
Antigène
Voir toutes TARDBP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-264
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Fonction
- TARDBP Antibody / TAR DNA binding protein / TDP43
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Purification
- Antigen affinity chromatography
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Immunogène
- An E.coli-derived human recombinant protein (amino acids M1-H264) was used as the immunogen for the TARDBP antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the TARDBP antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the TARDBP Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- TARDBP (TAR DNA Binding Protein (TARDBP))
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Autre désignation
- TARDBP
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Sujet
- HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
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UniProt
- Q13148
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Pathways
- Positive Regulation of Peptide Hormone Secretion
Antigène
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