AFT1 anticorps (AA 1-271)

N° du produit ABIN7869020

Cet anticorps Souris Monoclonal détecte spécifiquement AFT1 dans WB, IF, IHC (p) et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour AFT1 anticorps (AA 1-271) (ABIN7869020)

Antigène: AFT1 (Activating Transcription Factor 1 (AFT1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp AFT1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: 7F8

Détail du produit anti-AFT1 anticorps

Épitope: AA 1-271

Fonction: ATF1 Antibody

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids M1-V271) was used as the immunogen for the ATF1 antibody.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal dilution of the ATF1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the ATF1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur AFT1

Antigène: AFT1 (Activating Transcription Factor 1 (AFT1))

Autre désignation: ATF1

Sujet: ATF1, also known as activating transcription factor 1, is a protein that in humans is encoded by the ATF1 gene. It is mapped to 12q13.12. This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation.

UniProt: P18846

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades