Recombinant Calnexin anticorps (N-Term)
Aperçu rapide pour Recombinant Calnexin anticorps (N-Term) (ABIN7869160)
Antigène
Voir toutes Calnexin (CANX) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-300, N-Term
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Fonction
- Recombinant Calnexin Antibody
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Purification
- Protein A/G affinity
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Immunogène
- A recombinant N-terminal region fragment of human Calnexin protein (within amino acids 1-300) was used as the immunogen for the recombinant Calnexin antibody.
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Isotype
- IgG, kappa
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Indications d'application
- Optimal dilution of the recombinant Calnexin antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the recombinant Calnexin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Calnexin (CANX)
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Autre désignation
- Calnexin
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Sujet
- It recognizes a protein of 90 kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.
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UniProt
- P27824
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Pathways
- Signalisation MAPK, Thyroid Hormone Synthesis
Antigène
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