MRPL41 anticorps (AA 1-332)

N° du produit ABIN7869202

Cet anticorps anti-MRPL41 Polyclonal Lapin (ABIN7869202) détecte spécifiquement MRPL41 dans WB, ELISA et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour MRPL41 anticorps (AA 1-332) (ABIN7869202)

Antigène: MRPL41 (Mitochondrial Ribosomal Protein L41 (MRPL41))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MRPL41 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-MRPL41 anticorps

Épitope: AA 1-332

Fonction: PIG3 Antibody / TP53I3

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids M1-Q332) was used as the immunogen for the PIG3 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the PIG3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the PIG3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur MRPL41

Antigène: MRPL41 (Mitochondrial Ribosomal Protein L41 (MRPL41))

Autre désignation: PIG3

Sujet: Putative quinone oxidoreductase is an enzyme that in humans is encoded by the TP53I3 gene. The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniProt: Q53FA7

Pathways: Signalisation p53