GHITM anticorps (AA 1-345)

N° du produit ABIN7869226

Cet anticorps anti-GHITM Polyclonal Lapin (ABIN7869226) détecte spécifiquement GHITM dans ELISA, WB, IF, FACS et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GHITM anticorps (AA 1-345) (ABIN7869226)

Antigène: GHITM (Growth Hormone Inducible Transmembrane Protein (GHITM))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GHITM est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-GHITM anticorps

Épitope: AA 1-345

Fonction: GHITM Antibody / MICS1

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids M1-K345) was used as the immunogen for the GHITM antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the GHITM antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the GHITM antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur GHITM

Antigène: GHITM (Growth Hormone Inducible Transmembrane Protein (GHITM))

Autre désignation: GHITM

Sujet: Growth hormone-inducible transmembrane protein (GHITM), also known as transmembrane BAX inhibitor motif containing protein 5 (TMBIM5), is a protein that in humans is encoded by the GHITM gene on chromosome 10. GHITM, also known asMICS1, TMBIM5 or DERP2, is a mitochondrial protein which localizes in the inner membrane. GHITM is involved in mitochondrial morphology in specific cristae structures and the apoptotic release of cytochrome c from the mitochondria. The gene of GHITM maps to chromosome 10q23.1, and encodes a 345-amino-acid protein with a calculated molecular mass of 37 kDa. The apparent molecular weight has been reported to be 42 kDa, the increased size in the protein may be due to post-translational modifications. GHITM can be cleaved into smaller forms of 23-27 kDa.

UniProt: Q9H3K2

Pathways: SARS-CoV-2 Protein Interactome